Press Release

Replicor to disclose interim REP 2055 clinical efficacy data in patients with chronic hepatitis B at the 21st Conference of the Asian Pacific Association for the Study of the Liver (APASL 2011).

17-20 February 2011, QSNCC, Bangkok Thailand

February 17, 2011 – Replicor will disclose updated interim results from its proof of concept clinical trial at the 21st Conference of the Asian Pacific Association for the Study of the Liver (APASL 2011) currently being held from 17-20th of February. This is the largest annual meeting in South Asia dedicated to treatment of liver disease which typically attracts thousands of physicians and researchers. This trial is examining the safety and efficacy of REP 2055 in human patients with chronic hepatitis B (HBV).

REP 2055 represents a new class of antiviral agent that blocks the release of hepatitis B surface antigen (HBsAg) which has been associated with HBV-specific immune defects and may contribute to the long term persistence of HBV infection in the liver. REP 2055 has been previously shown to rapidly clear HBsAg in the serum of patients infected with HBV and appears to allow these patients to regain effective immunological control over their infection, resulting in sustained virologic responses after only 5-6 months of treatment. Replicor will present updated clinical efficacy results from an expanded population of patients in a poster presentation on Friday Feb 18th, 2011.

The 21st Conference of the Asian Pacific Association for the Study of the Liver.